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Molecular Mechanisms, Endurance Athlete, and Synergistic Therapeutic Effects of Marine‐Derived Antioxidant Astaxanthin Supplementation and Exercise in Cancer, Metabolic Diseases, and Healthy Individuals - Nie - 2025 - Food Science & Nutrition - Wiley ...

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Interestingly, some JAK2-activating mutations including V617F have been shown to require interaction with a cytokine receptor for their activity, suggesting that these mutations only disrupt inhibition of the pseudokinase when the JAK2 is bound to a receptor (90–93)